STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0615TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; sucrose-6F-phosphate phosphohydrolase; KEGG: kra:Krad_0255 HAD family hydrolase. (276 aa)    
Predicted Functional Partners:
Afer_0614
KEGG: pap:PSPA7_5451 hypothetical protein.
       0.777
Afer_0616
Hypothetical protein.
       0.682
Afer_0617
PFAM: inositol monophosphatase; KEGG: mth:MTH871 bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase.
  
  
 0.661
Afer_0618
PFAM: GCN5-related N-acetyltransferase; KEGG: afw:Anae109_1562 GCN5-related N- acetyltransferase.
  
    0.637
Afer_0613
KEGG: cti:RALTA_B0059 conserved hypothetical protein; putative exported protein; contains cristalline beta-sheet repeat similar to EBV nuclear antigen 1 (EBNA- 1) and fibroin.
       0.567
Afer_1123
PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; KEGG: tfu:Tfu_1394 mannose-1-phosphate guanylyltransferase.
  
  
 0.555
Afer_0611
KEGG: mpo:Mpop_0738 hypothetical protein.
       0.447
Afer_0612
PFAM: peptidase S45 penicillin amidase; KEGG: tac:Ta1462 penicillin amidase precursor related protein.
       0.447
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.439
Afer_1685
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.434
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.