STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0625RNA polymerase, sigma 28 subunit, FliA/WhiG; KEGG: ace:Acel_1546 RNA polymerase sigma factor WhiG; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; sigma- 70 region 3 domain protein. (254 aa)    
Predicted Functional Partners:
Afer_0135
PFAM: protein of unknown function DUF1078 domain protein; KEGG: kra:Krad_1648 hypothetical protein; Belongs to the flagella basal body rod proteins family.
 
 
 0.920
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.910
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.910
Afer_0150
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: ace:Acel_0854 flagellar motor switch protein FliM.
 
 
 0.897
Afer_0145
PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; flagellar basal body rod protein; KEGG: ace:Acel_0849 hypothetical protein.
 
  
 0.886
Afer_0138
TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; KEGG: ace:Acel_0842 flagellar motor switch protein FliG.
 
  
 0.881
Afer_0151
TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: ace:Acel_0855 flagellar motor switch protein FliN.
 
  
 0.880
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.876
Afer_0134
Flagellar basal body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
 
 0.858
Afer_0359
KEGG: hypothetical protein.
    
 
 0.858
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.