STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0648PFAM: cell division FtsK/SpoIIIE; SMART: AAA ATPase; KEGG: ace:Acel_1501 cell division FtsK/SpoIIIE. (724 aa)    
Predicted Functional Partners:
Afer_0647
PFAM: beta-lactamase domain protein; RNA- metabolising metallo-beta-lactamase; KEGG: swo:Swol_1268 metallo-beta-lactamase family protein.
 
    0.870
Afer_1400
KEGG: ace:Acel_1702 secreted protein.
  
 
 0.829
Afer_0652
TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: fal:FRAAL5732 competence-inducible (CinA- like) protein; Belongs to the CinA family.
     
 0.803
Afer_0071
Hypothetical protein; KEGG: fal:FRAAL5406 glycine-rich cell wall structural protein precursor (partial match).
   
 
 0.791
Afer_1929
Hypothetical protein; KEGG: aba:Acid345_0662 parallel beta-helix repeat protein.
   
 
 0.791
Afer_1977
Hypothetical protein; KEGG: aba:Acid345_3948 NHL repeat protein.
   
 
 0.791
Afer_2030
parB-like partition protein; KEGG: ace:Acel_2154 chromosome segregation DNA- binding protein; TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; Belongs to the ParB family.
  
  
 0.789
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.768
Afer_0624
PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sew:SeSA_A4159 tyrosine recombinase XerC.
 
   
 0.725
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.712
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.