Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0665PFAM: NMT1/THI5 like domain protein; KEGG: rpc:RPC_0844 ABC transporter substrate- binding protein. (333 aa)    
Predicted Functional Partners:
Afer_0666
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eba:p2A122 putative taurine transport system permease protein.
 
 
 0.996
Afer_0667
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mem:Memar_0849 ABC transporter-related protein.
 
 
 0.993
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
    0.819
Afer_1789
PFAM: regulatory protein TetR; KEGG: sgr:SGR_6910 TetR family transcriptional regulator.
  
     0.660
Afer_0668
SOS-response transcriptional repressor, LexA; KEGG: nfa:nfa38000 LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein; Belongs to the peptidase S24 family.
       0.656
Afer_0694
PFAM: major facilitator superfamily MFS_1; KEGG: ace:Acel_1472 major facilitator transporter.
  
     0.654
Afer_0503
PFAM: Extracellular ligand-binding receptor; KEGG: hwa:HQ3303A ABC-type branched-chain amino acid transport systems, substrate-binding protein.
  
  
 0.555
Afer_1159
PFAM: NADPH-dependent FMN reductase; KEGG: hau:Haur_2685 NAD(P)H dehydrogenase (quinone).
  
  
 0.548
Afer_1377
PFAM: ferredoxin; Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dar:Daro_0368 ferredoxin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region.
 
  
 0.547
Afer_0256
PFAM: metallophosphoesterase; KEGG: pzu:PHZ_c0307 3',5'-cyclic-nucleotide phosphodiesterase.
  
     0.496
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.