STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0668SOS-response transcriptional repressor, LexA; KEGG: nfa:nfa38000 LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24 and S26 domain protein; Belongs to the peptidase S24 family. (207 aa)    
Predicted Functional Partners:
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.987
Afer_1612
KEGG: fal:FRAAL2179 putative DNA-directed DNA polymerase.
  
 
 0.866
Afer_0666
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: eba:p2A122 putative taurine transport system permease protein.
 
     0.786
Afer_0667
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mem:Memar_0849 ABC transporter-related protein.
       0.752
Afer_1136
SMC domain protein; May be involved in recombinational repair of damaged DNA.
   
  
 0.735
Afer_1467
PFAM: Exonuclease RNase T and DNA polymerase III; Excinuclease ABC C subunit domain protein; UvrB/UvrC protein; SMART: Exonuclease; Excinuclease ABC C subunit domain protein; KEGG: ace:Acel_0968 hypothetical protein.
  
  
 0.735
Afer_0665
PFAM: NMT1/THI5 like domain protein; KEGG: rpc:RPC_0844 ABC transporter substrate- binding protein.
     
 0.663
nrdR
ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.659
argR
Arginine repressor, ArgR; Regulates arginine biosynthesis genes.
  
   
 0.611
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
   
 0.580
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.