STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0697Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: bbr:BB0978 gamma-glutamyltranspeptidase precursor. (524 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 0.925
Afer_1201
PFAM: glutathione peroxidase; KEGG: nfa:nfa46650 putative glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.917
Afer_1640
TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: bca:BCE_2691 glutamate decarboxylase; Belongs to the group II decarboxylase family.
     
 0.907
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.891
Afer_0243
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fre:Franean1_1770 glutamine synthetase, type I.
     
 0.874
Afer_0242
PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sat:SYN_01628 glutamine synthetase.
     
 0.863
Afer_1967
PFAM: glutamine synthetase catalytic region; KEGG: fra:Francci3_0315 L-glutamine synthetase.
     
 0.863
Afer_1378
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: ote:Oter_0715 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.816
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
    
  0.804
Afer_0272
PFAM: NAD-glutamate dehydrogenase; KEGG: ace:Acel_1749 glutamate dehydrogenase (NAD).
     
  0.800
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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