STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0705PFAM: beta-lactamase domain protein; KEGG: sen:SACE_5316 metallo-beta-lactamase superfamily protein. (201 aa)    
Predicted Functional Partners:
Afer_0704
PFAM: nitroreductase; KEGG: sdn:Sden_2315 nitroreductase.
       0.776
Afer_1014
PFAM: beta-lactamase domain protein; KEGG: nca:Noca_2937 beta-lactamase domain- containing protein.
 
 
 0.745
Afer_0702
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: nca:Noca_1614 ATPase domain-containing protein.
  
  
 0.624
Afer_0701
KEGG: scl:sce3939 hypothetical protein.
       0.620
Afer_0703
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: rha:RHA1_ro08012 response regulator, two- component system.
       0.620
Afer_0706
Hypothetical protein.
       0.532
Afer_1026
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerization region; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: cef:CE0339 putative pyridine nucleotide- disulphide oxidoreductase.
  
 0.445
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.