STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0716PFAM: aldo/keto reductase; KEGG: mpa:MAP3260 hypothetical protein. (306 aa)    
Predicted Functional Partners:
Afer_1306
PFAM: aldo/keto reductase; KEGG: nca:Noca_0658 aldo/keto reductase.
 
     0.730
Afer_0715
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xau:Xaut_4664 short-chain dehydrogenase/reductase SDR.
  
 
 0.652
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.603
Afer_0720
PFAM: peptidase M24; creatinase; KEGG: sma:SAV_2161 peptidase; Belongs to the peptidase M24B family.
  
    0.566
Afer_0717
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: ace:Acel_0936 dihydrolipoamide dehydrogenase.
  
    0.561
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.560
Afer_0718
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: fre:Franean1_1779 2-oxoglutarate dehydrogenase E2 component.
       0.553
Afer_0024
PFAM: histone deacetylase superfamily; KEGG: sul:SYO3AOP1_1212 histone deacetylase superfamily.
   
  0.550
Afer_0721
PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: mxa:MXAN_2995 peptidase, S1C (protease Do) subfamily.
  
    0.427
Afer_0875
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: sco:SCO4057 transport integral membrane protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.414
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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