Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0729PFAM: nitroreductase; KEGG: kra:Krad_1547 nitroreductase. (220 aa)    
Predicted Functional Partners:
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
     
 0.818
Afer_0730
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: kra:Krad_3912 carbamoyl-phosphate synthase L chain ATP-binding.
       0.773
Afer_1878
PFAM: ABC-2 type transporter; KEGG: fra:Francci3_1473 hypothetical protein.
 
    0.679
Afer_0731
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: rpb:RPB_3299 biotin--acetyl-CoA-carboxylase ligase.
  
    0.659
Afer_0344
PFAM: ABC-2 type transporter; KEGG: dra:DR_A0008 hypothetical protein.
 
    0.652
Afer_0732
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: ace:Acel_0405 butyryl-CoA dehydrogenase.
     
 0.557
Afer_0802
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: stp:Strop_2520 precorrin-3B C17- methyltransferase.
     
 0.545
Afer_1227
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: atc:AGR_C_1212 hypothetical protein.
 
  
 0.542
Afer_1338
Putative transcriptional regulator; SMART: regulatory protein ArsR; KEGG: stp:Strop_2302 regulatory protein, ArsR.
 
   
 0.520
Afer_0741
TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD; KEGG: rxy:Rxyl_0958 LPPG:Fo 2-phospho-L-lactate transferase.
 
  
 0.509
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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