STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0731TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; KEGG: rpb:RPB_3299 biotin--acetyl-CoA-carboxylase ligase. (258 aa)    
Predicted Functional Partners:
Afer_0730
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: kra:Krad_3912 carbamoyl-phosphate synthase L chain ATP-binding.
 
  
 0.945
Afer_1724
KEGG: ank:AnaeK_1423 protein of unknown function DUF201.
  
 0.913
Afer_1052
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cts:Ctha_0126 radical SAM domain protein.
     
  0.900
Afer_1032
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: fal:FRAAL1668 acetyl-/propionyl-coenzyme A carboxylase alpha chain.
 
  
 0.877
Afer_0732
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: ace:Acel_0405 butyryl-CoA dehydrogenase.
  
    0.780
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
     
 0.738
Afer_0733
TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: fal:FRAAL1228 glucose-1-phosphate thymidylyltransferase (dTDP-glucose synthase) (dTDP- glucose pyrophosphorylase) (sugar-nucleotidylation enzyme).
       0.694
Afer_0728
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: mxa:MXAN_2588 molybdopterin biosynthesis protein MoeB.
  
    0.673
Afer_0729
PFAM: nitroreductase; KEGG: kra:Krad_1547 nitroreductase.
  
    0.666
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.659
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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