STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0749PFAM: bifunctional deaminase-reductase domain protein; KEGG: ace:Acel_1375 deaminase-reductase domain- containing protein. (221 aa)    
Predicted Functional Partners:
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.934
Afer_0748
KEGG: LOC100072155; hypothetical protein LOC100072155.
       0.773
Afer_1684
PFAM: Lumazine-binding protein; KEGG: tfu:Tfu_1078 riboflavin synthase subunit alpha.
  
  
 0.746
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.739
Afer_1837
PFAM: protein of unknown function DUF75; KEGG: kra:Krad_1842 hypothetical protein.
  
     0.639
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
  
    0.572
Afer_0641
TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; KEGG: lxx:Lxx07280 riboflavin kinase/FMN adenyltransferase; Belongs to the ribF family.
  
  
 0.557
Afer_0860
PFAM: Luciferase-like monooxygenase; KEGG: sco:SCO6786 oxidoreductase.
  
   
 0.496
Afer_0764
TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: dra:DR_2575 folyl-polyglutamate synthetase.
     
 0.491
Afer_0454
KEGG: tfu:Tfu_2983 hypothetical protein.
  
     0.487
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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