STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0757KEGG: sgr:SGR_5851 hypothetical protein. (259 aa)    
Predicted Functional Partners:
Afer_0756
PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: fra:Francci3_3059 phosphoesterase, PA- phosphatase related.
       0.816
Afer_0758
PFAM: alpha/beta hydrolase fold; KEGG: predicted protein.
       0.805
Afer_0755
PFAM: NUDIX hydrolase; KEGG: stp:Strop_1261 NUDIX hydrolase.
       0.773
Afer_0038
PFAM: transcriptional regulator PadR family protein; KEGG: fra:Francci3_4528 PadR family transcriptional regulator.
  
     0.681
Afer_1448
KEGG: fre:Franean1_0153 major facilitator transporter.
  
     0.655
pafA
Protein of unknown function DUF245 domain protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
 
   
 0.625
Afer_0754
PFAM: DSBA oxidoreductase; KEGG: fal:FRAAL2315 hypothetical protein.
       0.605
Afer_0759
PFAM: SNARE associated Golgi protein; KEGG: ank:AnaeK_1303 SNARE associated Golgi protein.
       0.570
Afer_0908
PFAM: protein of unknown function DUF245 domain protein; protein of unknown function DUF275 domain protein; KEGG: fra:Francci3_2629 hypothetical protein.
 
     0.558
Afer_0244
KEGG: kra:Krad_4317 hypothetical protein.
  
     0.480
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.