STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0769Penicillin-binding protein 2; KEGG: fre:Franean1_5266 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain. (644 aa)    
Predicted Functional Partners:
Afer_0956
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: nca:Noca_3461 rod shape-determining protein RodA; Belongs to the SEDS family.
 
 0.989
Afer_0767
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.954
Afer_0766
TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA; KEGG: fre:Franean1_5269 cell shape determining protein MreB.
 
 
 0.939
Afer_0089
PFAM: penicillin-binding protein transpeptidase; KEGG: ace:Acel_0020 peptidoglycan glycosyltransferase.
  
  
 
0.928
Afer_1250
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ace:Acel_1004 peptidoglycan glycosyltransferase.
  
  
 
0.926
Afer_1246
PFAM: cell cycle protein; KEGG: nfa:nfa17650 putative cell division protein; Belongs to the SEDS family.
 
 0.922
Afer_1003
PFAM: cell cycle protein; KEGG: fal:FRAAL6752 putative cell division protein FtsW; Belongs to the SEDS family.
 
 0.826
Afer_1886
Actin-like ATPase involved in cell morphogenesis; KEGG: cbf:CLI_0218 mbl protein.
 
 
 
 0.819
Afer_0768
TIGRFAM: rod shape-determining protein MreD; KEGG: aoe:Clos_1763 hypothetical protein.
  
  
 0.695
murE-2
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
  
 0.558
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.