STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_07865-carboxymethyl-2-hydroxymuconateDelta- isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: fal:FRAAL6170 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase (HhdD isomerase)/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase). (286 aa)    
Predicted Functional Partners:
Afer_0812
PFAM: homogentisate 12-dioxygenase; KEGG: stp:Strop_4258 homogentisate 1,2-dioxygenase.
  
  
 0.680
Afer_0787
Hypothetical protein.
       0.651
Afer_1378
PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; KEGG: ote:Oter_0715 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.555
Afer_0785
Hypothetical protein; KEGG: cbe:Cbei_2588 collagen triple helix repeat.
       0.497
Afer_0788
TIGRFAM: yecA family protein; KEGG: cli:Clim_0950 YecA family protein.
       0.453
Afer_0094
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: nfa:nfa21550 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
 
 0.406
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.