Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0798PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce5736 AMP-dependent synthetase and ligase. (552 aa)    
Predicted Functional Partners:
Afer_0797
PFAM: acyl-ACP thioesterase; KEGG: nfa:nfa20140 hypothetical protein.
       0.775
Afer_0799
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: sco:SCO1858 hypothetical protein.
       0.601
Afer_0800
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: rxy:Rxyl_0645 precorrin-8X methylmutase.
       0.601
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
      0.559
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.542
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.535
acpP-2
Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.535
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.530
rplX
Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
    
   0.522
Afer_1770
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: lic:LIC13009 acyl-CoA dehydrogenase.
  
 
 0.522
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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