STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0811Endothelin-converting enzyme 1; PFAM: peptidase M13; peptidase M13 neprilysin; KEGG: lxx:Lxx01010 metallopeptidase. (658 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.770
Afer_0493
PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: ank:AnaeK_2441 peptidase M1 membrane alanine aminopeptidase.
 
   
 0.621
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
   
    0.559
Afer_0812
PFAM: homogentisate 12-dioxygenase; KEGG: stp:Strop_4258 homogentisate 1,2-dioxygenase.
       0.538
Afer_0813
PFAM: beta-lactamase domain protein; KEGG: sen:SACE_4081 beta lactamase.
       0.538
Afer_0814
PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sen:SACE_3057 pentachlorophenol monooxygenase.
       0.538
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.524
Afer_0071
Hypothetical protein; KEGG: fal:FRAAL5406 glycine-rich cell wall structural protein precursor (partial match).
  
    0.478
Afer_1400
KEGG: ace:Acel_1702 secreted protein.
  
    0.478
Afer_1929
Hypothetical protein; KEGG: aba:Acid345_0662 parallel beta-helix repeat protein.
  
    0.478
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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