STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0812PFAM: homogentisate 12-dioxygenase; KEGG: stp:Strop_4258 homogentisate 1,2-dioxygenase. (393 aa)    
Predicted Functional Partners:
Afer_0803
Fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: fre:Franean1_3789 fumarylacetoacetase.
  
 0.975
Afer_1033
PFAM: protein of unknown function DUF1446; KEGG: mjl:Mjls_3217 hypothetical protein.
  
 
 0.848
Afer_0814
PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sen:SACE_3057 pentachlorophenol monooxygenase.
  
  
 0.844
Afer_0813
PFAM: beta-lactamase domain protein; KEGG: sen:SACE_4081 beta lactamase.
  
    0.803
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.752
Afer_0786
5-carboxymethyl-2-hydroxymuconateDelta- isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: fal:FRAAL6170 2-hydroxyhepta-2,4-diene-1,7- dioate isomerase (HhdD isomerase)/5-carboxymethyl-2-oxo- hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase).
  
  
 0.680
Afer_0817
KEGG: nfa:nfa40830 putative magnesium chelatase subunit; PFAM: ATPase associated with various cellular activities AAA_5; AAA ATPase central domain protein; von Willebrand factor type A; magnesium chelatase ChlI subunit; SMART: von Willebrand factor type A; AAA ATPase.
  
    0.630
Afer_0727
KEGG: cau:Caur_3165 transcriptional coactivator/pterin dehydratase.
  
  
 0.600
Afer_0816
Cobaltochelatase, CobN subunit; KEGG: rxy:Rxyl_0635 cobaltochelatase; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase.
       0.596
Afer_0811
Endothelin-converting enzyme 1; PFAM: peptidase M13; peptidase M13 neprilysin; KEGG: lxx:Lxx01010 metallopeptidase.
       0.538
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (26%) [HD]