Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0814PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: sen:SACE_3057 pentachlorophenol monooxygenase. (525 aa)    
Predicted Functional Partners:
Afer_0813
PFAM: beta-lactamase domain protein; KEGG: sen:SACE_4081 beta lactamase.
  
 0.979
Afer_0812
PFAM: homogentisate 12-dioxygenase; KEGG: stp:Strop_4258 homogentisate 1,2-dioxygenase.
  
  
 0.876
Afer_0490
PFAM: Methyltransferase type 11; Methionine biosynthesis MetW protein; Methyltransferase type 12; KEGG: tfu:Tfu_0572 hypothetical protein.
  
 0.774
Afer_0601
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: esa:ESA_03129 hypothetical protein.
  
 0.774
Afer_1936
PFAM: Methyltransferase type 11; Tellurite resistance methyltransferase, TehB, core; Methyltransferase type 12; KEGG: ace:Acel_0489 methyltransferase type 12.
  
 0.774
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.752
Afer_1344
PFAM: beta-lactamase domain protein; KEGG: sma:SAV_6616 polyketide cyclase.
  
  
 0.615
Afer_0817
KEGG: nfa:nfa40830 putative magnesium chelatase subunit; PFAM: ATPase associated with various cellular activities AAA_5; AAA ATPase central domain protein; von Willebrand factor type A; magnesium chelatase ChlI subunit; SMART: von Willebrand factor type A; AAA ATPase.
  
  
 0.609
Afer_0816
Cobaltochelatase, CobN subunit; KEGG: rxy:Rxyl_0635 cobaltochelatase; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase.
     
 0.602
Afer_1092
PFAM: ABC-1 domain protein; aminoglycoside phosphotransferase; KEGG: mab:MAB_2393c hypothetical protein.
   
 0.583
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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