STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0821TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: dge:Dgeo_2746 formate dehydrogenase, alpha subunit. (985 aa)    
Predicted Functional Partners:
Afer_0367
TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: msm:MSMEG_2059 NADH-quinone oxidoreductase chain E.
  
 
 0.949
Afer_0822
KEGG: sgr:SGR_1901 putative chromosome segregation protein.
  
  
 0.923
Afer_1987
TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mkm:Mkms_5153 glutamate synthase subunit beta.
    
 0.911
Afer_0368
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mxa:MXAN_1085 NADH dehydrogenase I, F subunit.
 
 0.907
Afer_1021
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Polysulphide reductase NrfD; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
 0.907
Afer_0998
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: sco:SCP1.160c putative oxidoreductase.
 
 
 0.904
Afer_0834
PFAM: formate dehydrogenase subunit FdhD; KEGG: ttj:TTHB196 putative protein required for formate dehydrogenase activity.
 
 
 0.872
Afer_1450
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dsy:DSY3404 hypothetical protein.
    
 0.832
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.822
Afer_0622
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; KEGG: nca:Noca_0113 malate dehydrogenase.
    
 0.808
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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