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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Afer_0824PFAM: Transketolase central region; Transketolase domain protein; KEGG: gka:GK3216 pyruvate dehydrogenase E1 (lipoamide) beta subunit. (326 aa)    
Predicted Functional Partners:
Afer_0823
KEGG: hsl:OE4113F putative branched-chain amino acid dehydrogenase E1 component alpha subunit; TIGRFAM: pyruvate dehydrogenase (acetyl- transferring) E1 component, alpha subunit; PFAM: dehydrogenase E1 component.
 0.999
Afer_0825
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sth:STH413 pyruvate dehydrogenase E2.
 0.999
Afer_0718
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: fre:Franean1_1779 2-oxoglutarate dehydrogenase E2 component.
 0.998
Afer_0826
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: gka:GK1061 dihydrolipoamide dehydrogenase.
 0.996
Afer_1732
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: ace:Acel_0586 alpha-ketoglutarate decarboxylase.
  
 0.996
Afer_0717
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: ace:Acel_0936 dihydrolipoamide dehydrogenase.
 0.991
Afer_0293
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: min:Minf_1201 pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme.
 
 0.990
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.955
Afer_1947
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; UBA/THIF- type NAD/FAD binding protein; KEGG: rxy:Rxyl_1110 malate dehydrogenase (oxaloacetate decarboxylating).
  
 
 0.941
Afer_0622
Malate dehydrogenase (oxaloacetate- decarboxylating); PFAM: malic protein NAD-binding; amino acid-binding ACT domain protein; malic protein domain protein; KEGG: nca:Noca_0113 malate dehydrogenase.
   
 
 0.938
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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