Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0828PFAM: conserved hypothetical protein; KEGG: rxy:Rxyl_2377 conserved hypothetical protein 374. (339 aa)    
Predicted Functional Partners:
Afer_0827
KEGG: fal:FRAAL3473 putative acetyl-CoA hydrolase.
       0.705
Afer_1023
KEGG: afw:Anae109_1828 hypothetical protein.
 
     0.693
Afer_0797
PFAM: acyl-ACP thioesterase; KEGG: nfa:nfa20140 hypothetical protein.
  
     0.640
Afer_0855
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: afe:Lferr_1745 hypothetical protein.
 
     0.572
Afer_1562
PFAM: protein of unknown function DUF501; KEGG: rxy:Rxyl_0915 hypothetical protein.
  
     0.571
Afer_0577
KEGG: oih:OB1441 hypothetical protein.
  
     0.551
Afer_1195
KEGG: scl:sce0507 hypothetical protein.
  
     0.538
Afer_0784
PFAM: VWA containing CoxE family protein; KEGG: fre:Franean1_5254 VWA containing CoxE family protein.
  
     0.525
Afer_0829
PFAM: protein of unknown function UPF0118; KEGG: kra:Krad_0518 hypothetical protein.
 
   
 0.525
Afer_1451
Cyclic nucleotide-binding protein; KEGG: mse:Msed_0469 hypothetical protein.
  
     0.514
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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