STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0834PFAM: formate dehydrogenase subunit FdhD; KEGG: ttj:TTHB196 putative protein required for formate dehydrogenase activity. (269 aa)    
Predicted Functional Partners:
Afer_0821
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: dge:Dgeo_2746 formate dehydrogenase, alpha subunit.
 
 
 0.872
Afer_1021
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Polysulphide reductase NrfD; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
   
 0.803
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.675
Afer_0835
KEGG: saq:Sare_3891 hypothetical protein.
       0.552
Afer_1020
PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; KEGG: cau:Caur_3201 nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.526
Afer_0486
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
   
 0.502
Afer_1884
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: mem:Memar_1334 molybdopterin biosynthesis MoaE.
 
  
 0.479
Afer_1852
Hypothetical protein; KEGG: mmr:Mmar10_2710 molybdenum cofactor guanylyltransferase.
   
 
 0.411
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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