STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0838PFAM: MscS Mechanosensitive ion channel; KEGG: bcm:Bcenmc03_1911 MscS mechanosensitive ion channel. (374 aa)    
Predicted Functional Partners:
Afer_1849
PFAM: glycosyl transferase family 20; KEGG: sco:SCO4290 trehalose-phosphate synthase.
 
   
 0.723
Afer_0770
TIGRFAM: ribonuclease, Rne/Rng family; KEGG: tfu:Tfu_2183 ribonuclease E and G.
 
      0.696
Afer_1850
TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; trehalose-phosphatase; PFAM: trehalose-phosphatase; KEGG: saq:Sare_0810 HAD family hydrolase.
 
  
 0.632
Afer_0495
PFAM: glycoside hydrolase 15-related; KEGG: ote:Oter_3331 glycoside hydrolase 15-related.
 
    0.628
Afer_0839
PFAM: MaoC domain protein dehydratase; KEGG: sma:SAV_6603 hypothetical protein.
       0.548
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
      0.540
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
    0.505
Afer_0840
Polyphosphate:AMP phosphotransferase; PFAM: protein of unknown function DUF344; KEGG: mpt:Mpe_A3289 polyphosphate:AMP phosphotransferase.
  
    0.498
Afer_0841
Hypothetical protein.
       0.477
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.458
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.