Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Afer_0839PFAM: MaoC domain protein dehydratase; KEGG: sma:SAV_6603 hypothetical protein. (153 aa)    
Predicted Functional Partners:
Afer_0197
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: tth:TTC1833 quinone oxidoreductase.
 
 
 0.871
Afer_0841
Hypothetical protein.
  
   0.811
Afer_1787
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: msm:MSMEG_3306 zinc-binding alcohol dehydrogenase.
 
 0.801
Afer_0840
Polyphosphate:AMP phosphotransferase; PFAM: protein of unknown function DUF344; KEGG: mpt:Mpe_A3289 polyphosphate:AMP phosphotransferase.
       0.677
Afer_1493
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sma:SAV_3829 enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.597
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
 0.553
Afer_0843
PFAM: Chorismate binding-like; KEGG: bcj:BCAM2235 putative pyochelin biosynthetic protein PchA.
       0.551
Afer_0838
PFAM: MscS Mechanosensitive ion channel; KEGG: bcm:Bcenmc03_1911 MscS mechanosensitive ion channel.
       0.546
Afer_1373
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: krh:KRH_02100 putative enoyl-CoA hydratase PaaG.
 
 0.538
Afer_0846
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: bbt:BBta_2180 putative methyltransferase.
     
 0.521
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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