Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0841Hypothetical protein. (66 aa)    
Predicted Functional Partners:
Afer_0085
KEGG: rrs:RoseRS_2545 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.862
Afer_0106
KEGG: fal:FRAAL5910 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.862
Afer_0261
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: tfu:Tfu_0436 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.862
Afer_1370
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: stp:Strop_1359 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.862
Afer_0839
PFAM: MaoC domain protein dehydratase; KEGG: sma:SAV_6603 hypothetical protein.
  
   0.811
Afer_0840
Polyphosphate:AMP phosphotransferase; PFAM: protein of unknown function DUF344; KEGG: mpt:Mpe_A3289 polyphosphate:AMP phosphotransferase.
       0.776
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
  
    0.619
Afer_0843
PFAM: Chorismate binding-like; KEGG: bcj:BCAM2235 putative pyochelin biosynthetic protein PchA.
       0.612
Afer_0846
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: bbt:BBta_2180 putative methyltransferase.
  
    0.608
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.601
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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