STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0868PFAM: DoxX family protein; KEGG: dge:Dgeo_2087 DoxX. (130 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
       0.546
Afer_1772
PFAM: peptidase C60 sortase A and B; KEGG: kra:Krad_3106 peptidase C60 sortase A and B.
  
     0.544
Afer_0866
Hypothetical protein.
       0.491
Afer_0867
PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: bph:Bphy_6281 permease for cytosine/purines uracil thiamine allantoin; Belongs to the purine-cytosine permease (2.A.39) family.
       0.491
Afer_0869
Hypothetical protein.
       0.441
Afer_1685
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.433
Afer_0870
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mbn:Mboo_0434 protein kinase.
       0.426
Afer_0872
PFAM: amino acid permease-associated region; KEGG: mbn:Mboo_0439 amino acid permease-associated region.
 
     0.415
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.