Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0870PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; SMART: serine/threonine protein kinase; tyrosine protein kinase; KEGG: mbn:Mboo_0434 protein kinase. (328 aa)    
Predicted Functional Partners:
Afer_0873
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: dra:DR_2513 hypothetical protein.
 
 0.952
Afer_0090
PFAM: Stage II sporulation E family protein; Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: nfa:nfa840 putative protein phosphatase.
 
 0.935
Afer_0869
Hypothetical protein.
       0.741
Afer_0092
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: art:Arth_0026 FHA domain containing protein.
 
 
 
 0.684
Afer_0871
PFAM: glutamine synthetase catalytic region; KEGG: blj:BLD_0159 glutamine synthetase.
     
 0.682
Afer_1125
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: ace:Acel_1226 FHA domain-containing protein.
 
 
 
 0.668
Afer_0091
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: cef:CE0038 hypothetical protein.
 
 
 
 0.622
Afer_1191
KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein.
 
  
 0.544
Afer_0201
Histidine kinase; KEGG: tfu:Tfu_2909 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
    
 0.438
Afer_0868
PFAM: DoxX family protein; KEGG: dge:Dgeo_2087 DoxX.
       0.426
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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