Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0889PFAM: FAD dependent oxidoreductase; KEGG: sgr:SGR_1833 putative FAD-dependent oxidoreductase. (487 aa)    
Predicted Functional Partners:
Afer_0574
PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: sgr:SGR_1846 AsnC family transcriptional regulator.
 
  
 0.797
Afer_0575
PFAM: aminotransferase class-III; KEGG: ace:Acel_1287 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.789
Afer_0886
PFAM: extracellular solute-binding protein family 5; KEGG: saq:Sare_4778 extracellular solute-binding protein.
       0.775
Afer_0887
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sco:SCO6113 peptide ABC transporter integral membrane protein.
       0.775
Afer_0888
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: saq:Sare_4780 binding-protein-dependent transport systems inner membrane component.
       0.773
Afer_0890
KEGG: stp:Strop_4339 oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; Belongs to the ABC transporter superfamily.
  
    0.753
Afer_0885
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: saq:Sare_4780 binding-protein-dependent transport systems inner membrane component.
       0.664
Afer_2005
KEGG: mva:Mvan_1847 hypothetical protein.
  
     0.629
Afer_1120
TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mgi:Mflv_2939 glycine cleavage system aminomethyltransferase T.
  
 
 0.574
Afer_1190
PFAM: aminotransferase class-III; KEGG: sen:SACE_3329 adenosylmethionine-8-amino-7- oxononanoate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.471
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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