Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_0938PFAM: cyclase/dehydrase; KEGG: fal:FRAAL0171 hypothetical protein. (160 aa)    
Predicted Functional Partners:
Afer_0937
PFAM: glycosyl transferase group 1; KEGG: rxy:Rxyl_0383 glycosyl transferase, group 1.
  
    0.757
Afer_1448
KEGG: fre:Franean1_0153 major facilitator transporter.
  
     0.735
Afer_0237
PFAM: Anion-transporting ATPase; KEGG: rha:RHA1_ro04317 arsenate (2+)-transporting ATPase.
 
    0.708
Afer_0350
ATPase involved in chromosome partitioning; KEGG: fre:Franean1_0335 anion-transporting ATPase.
 
    0.705
Afer_0193
PFAM: cytochrome oxidase assembly; KEGG: fra:Francci3_1653 cytochrome oxidase assembly.
    
  0.661
Afer_1690
Hypothetical protein; KEGG: lch:Lcho_0048 electron transport protein SCO1/SenC.
   
 
 0.611
Afer_0238
PFAM: Anion-transporting ATPase; KEGG: ank:AnaeK_0988 chromosome partitioning-like ATPase.
 
    0.609
Afer_1997
PFAM: ribonuclease BN; KEGG: ace:Acel_1654 ribonuclease BN.
  
     0.576
Afer_1693
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
   
 
  0.555
Afer_0939
PFAM: aminotransferase class I and II; KEGG: aae:aq_2094 aminotransferase.
       0.538
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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