STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0942TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: sen:SACE_5185 methylmalonate-semialdehyde dehydrogenase (acylating). (495 aa)    
Predicted Functional Partners:
Afer_1286
TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: ace:Acel_1984 acetyl-coenzyme A synthetase.
   
 0.933
Afer_1641
PFAM: AMP-dependent synthetase and ligase; KEGG: tac:Ta0769 acetyl-coenzyme A synthetase.
   
 0.933
Afer_0700
PFAM: aminotransferase class-III; KEGG: rca:Rcas_3219 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.932
Afer_1010
TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: dsh:Dshi_2319 quinone oxidoreductase putative YhdH/YhfP.
   
 0.913
Afer_0085
KEGG: rrs:RoseRS_2545 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.911
Afer_0106
KEGG: fal:FRAAL5910 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.911
Afer_0261
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: tfu:Tfu_0436 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.911
Afer_1370
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: stp:Strop_1359 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.911
Afer_0231
PFAM: carboxyl transferase; KEGG: rca:Rcas_4102 carboxyl transferase.
   
 0.908
Afer_0582
PFAM: carboxyl transferase; KEGG: saq:Sare_0802 carboxyl transferase.
   
 0.908
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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