Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0963PFAM: DsrE family protein; KEGG: afu:AF0187 hypothetical protein. (127 aa)    
Predicted Functional Partners:
Afer_0964
KEGG: cts:Ctha_0138 hypothetical protein.
 
   
 0.955
Afer_0965
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: cts:Ctha_0137 protein of unknown function DUF224 cysteine-rich region domain protein.
 
  
 0.955
Afer_0966
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cts:Ctha_0136 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
     0.948
Afer_0968
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: cts:Ctha_0133 protein of unknown function DUF224 cysteine-rich region domain protein.
 
     0.817
Afer_0969
PFAM: Electron transfer flavoprotein alpha/beta- subunit; KEGG: cts:Ctha_0132 electron transfer flavoprotein alpha/beta-subunit.
 
     0.794
Afer_0962
PFAM: SirA family protein; KEGG: sso:SSO8861 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
 
   
 0.788
Afer_0967
KEGG: cts:Ctha_0134 hypothetical protein.
       0.772
Afer_1056
PFAM: biotin/lipoate A/B protein ligase; KEGG: cts:Ctha_0125 biotin/lipoate A/B protein ligase.
 
     0.769
Afer_1052
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cts:Ctha_0126 radical SAM domain protein.
 
   
 0.760
Afer_0971
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: bph:Bphy_5959 hypothetical protein.
 
     0.759
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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