STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0988TIGRFAM: CRISPR-associated protein, Cse1 family; KEGG: sgr:SGR_3542 putative CRISPR-associated helicase Cas3 family protein protein (540 aa)    
Predicted Functional Partners:
Afer_0989
CRISPR-associated helicase Cas3; KEGG: fal:FRAAL0452 hypothetical protein; TIGRFAM: CRISPR-associated helicase Cas3; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases
     0.987
cas1
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
 
  
 0.981
Afer_0985
TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: fra:Francci3_0021 CRISPR-associated Cas5e family protein
 
 
 0.981
Afer_0986
TIGRFAM: CRISPR-associated protein, Cse4 family; KEGG: saq:Sare_2575 CRISPR-associated CSE4 family protein
 
 
 0.981
Afer_0982
TIGRFAM: CRISPR-associated protein Cas2; KEGG: sgr:SGR_3548 putative CRISPR-associated Cas2 family protein
 
   
 0.967
Afer_0984
TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: saq:Sare_2577 CRISPR-associated CSE3 family protein
 
     0.967
Afer_0987
TIGRFAM: CRISPR-associated protein, Cse2 family; KEGG: fra:Francci3_0019 hypothetical protein
 
     0.967
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
      
 0.728
Afer_0990
Uncharacterized protein; KEGG: mkm:Mkms_5906 integrase, catalytic region
       0.508
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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