Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_0994PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: acr:Acry_1366 periplasmic binding protein/LacI transcriptional regulator. (349 aa)    
Predicted Functional Partners:
Afer_0993
Monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; KEGG: rxy:Rxyl_0947 inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
 0.998
Afer_0992
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: msm:MSMEG_1372 ABC transporter ATP-binding protein.
 
 
 0.976
Afer_1574
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mva:Mvan_5292 ABC transporter-related protein.
 
 
 0.951
Afer_1577
Histidine kinase; PFAM: ABC transporter related; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; AAA ATPase; KEGG: sgr:SGR_1497 putative ABC transporter ATP- binding protein.
 
 
 0.920
Afer_0217
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: kra:Krad_0325 response regulator receiver protein.
   
 
 0.871
Afer_0995
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: cmi:CMM_2841 LacI family transcriptional regulator.
 
  
 0.861
Afer_0996
PFAM: PfkB domain protein; KEGG: saq:Sare_3490 ribokinase-like domain- containing protein.
 
  
 0.851
Afer_1575
KEGG: ace:Acel_1132 solute-binding protein.
 
  
 0.841
Afer_1573
PFAM: inner-membrane translocator; KEGG: saq:Sare_4238 monosaccharide-transporting ATPase; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.814
Afer_0702
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: nca:Noca_1614 ATPase domain-containing protein.
    
 
 0.813
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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