Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1002PFAM: biotin/lipoate A/B protein ligase; KEGG: cts:Ctha_0125 biotin/lipoate A/B protein ligase. (362 aa)    
Predicted Functional Partners:
Afer_1055
PFAM: glycine cleavage H-protein; KEGG: sto:ST1894 glycine cleavage system H protein.
 
 
 0.848
Afer_1003
PFAM: cell cycle protein; KEGG: fal:FRAAL6752 putative cell division protein FtsW; Belongs to the SEDS family.
       0.773
Afer_0965
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: cts:Ctha_0137 protein of unknown function DUF224 cysteine-rich region domain protein.
 
     0.771
Afer_0964
KEGG: cts:Ctha_0138 hypothetical protein.
 
     0.768
Afer_0966
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cts:Ctha_0136 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
     0.766
Afer_1052
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cts:Ctha_0126 radical SAM domain protein.
 
     0.757
Afer_1054
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cts:Ctha_0127 radical SAM domain protein.
 
     0.754
gcvH
Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.734
Afer_0963
PFAM: DsrE family protein; KEGG: afu:AF0187 hypothetical protein.
 
     0.704
Afer_0825
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sth:STH413 pyruvate dehydrogenase E2.
 
 0.634
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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