Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1003PFAM: cell cycle protein; KEGG: fal:FRAAL6752 putative cell division protein FtsW; Belongs to the SEDS family. (444 aa)    
Predicted Functional Partners:
Afer_0089
PFAM: penicillin-binding protein transpeptidase; KEGG: ace:Acel_0020 peptidoglycan glycosyltransferase.
 
 0.995
Afer_1246
PFAM: cell cycle protein; KEGG: nfa:nfa17650 putative cell division protein; Belongs to the SEDS family.
  
  
0.931
Afer_1250
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain; KEGG: ace:Acel_1004 peptidoglycan glycosyltransferase.
 
 0.928
Afer_0956
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: nca:Noca_3461 rod shape-determining protein RodA; Belongs to the SEDS family.
  
  
 
0.925
Afer_0769
Penicillin-binding protein 2; KEGG: fre:Franean1_5266 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerization domain.
 
 0.813
Afer_1245
Undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; KEGG: pzu:PHZ_c2323 UDP-N-acetylglucosamine--N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N- acetylglucosamine transferase.
 
  
 0.791
Afer_1002
PFAM: biotin/lipoate A/B protein ligase; KEGG: cts:Ctha_0125 biotin/lipoate A/B protein ligase.
       0.773
Afer_0873
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: dra:DR_2513 hypothetical protein.
  
 0.745
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.742
Afer_0091
FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; KEGG: cef:CE0038 hypothetical protein.
 
   
 0.713
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.