STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1007PFAM: FAD linked oxidase domain protein; KEGG: mmi:MMAR_0388 oxidoreductase. (445 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
  
 0.510
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: nfa:nfa49980 glucose-6-phosphate isomerase; Belongs to the GPI family.
     
 0.492
Afer_1010
TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: dsh:Dshi_2319 quinone oxidoreductase putative YhdH/YhfP.
     
 0.491
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.490
Afer_0354
PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: ace:Acel_0685 electron transfer flavoprotein, alpha subunit.
 
 
 0.445
Afer_0970
PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; KEGG: cts:Ctha_0131 electron transfer flavoprotein alpha subunit.
 
 
 0.445
Afer_1012
Putative signal transduction protein; PFAM: Metal-dependent hydrolase HDOD; KEGG: dar:Daro_1978 HDIG.
       0.445
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.432
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
     
 0.421
Afer_1360
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ank:AnaeK_2951 protein of unknown function DUF224 cysteine-rich region domain protein.
 
  
 0.403
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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