Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1014PFAM: beta-lactamase domain protein; KEGG: nca:Noca_2937 beta-lactamase domain- containing protein. (454 aa)    
Predicted Functional Partners:
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.851
rpsQ
Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.823
Afer_0428
PFAM: tRNA pseudouridine synthase; KEGG: tfu:Tfu_2616 tRNA pseudouridine synthase A.
   
 
 0.808
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
   
   0.785
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.778
acpP-2
Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.778
Afer_0705
PFAM: beta-lactamase domain protein; KEGG: sen:SACE_5316 metallo-beta-lactamase superfamily protein.
 
 
 0.733
Afer_1082
PFAM: beta-lactamase domain protein; KEGG: saq:Sare_1808 beta-lactamase domain- containing protein.
 
 
 0.682
Afer_0162
PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; KEGG: rha:RHA1_ro11237 sulfurtransferase, rhodanese related.
 
 
 0.636
Afer_1015
Hypothetical protein; KEGG: rxy:Rxyl_1675 carbohydrate kinase, FGGY.
       0.634
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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