Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1021PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Polysulphide reductase NrfD; KEGG: nca:Noca_2933 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein. (512 aa)    
Predicted Functional Partners:
Afer_1020
PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; KEGG: cau:Caur_3201 nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.998
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
 
 0.893
Afer_0821
TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: dge:Dgeo_2746 formate dehydrogenase, alpha subunit.
 
  
 0.890
Afer_1019
Hypothetical protein; KEGG: cau:Caur_3200 uncharacterized component of anaerobic dehydrogenase-like protein.
  
  
 0.872
Afer_1988
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: ace:Acel_1078 glutamate synthase (NADH) large subunit.
  
  
 0.782
Afer_0554
PFAM: restriction endonuclease; KEGG: ace:Acel_0036 restriction endonuclease.
   
    0.764
Afer_0971
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; KEGG: bph:Bphy_5959 hypothetical protein.
 
  
 0.682
Afer_0834
PFAM: formate dehydrogenase subunit FdhD; KEGG: ttj:TTHB196 putative protein required for formate dehydrogenase activity.
 
   
 0.629
Afer_1451
Cyclic nucleotide-binding protein; KEGG: mse:Msed_0469 hypothetical protein.
  
  
 0.628
Afer_0966
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cts:Ctha_0136 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
   
 0.606
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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