Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Afer_1032PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: fal:FRAAL1668 acetyl-/propionyl-coenzyme A carboxylase alpha chain. (646 aa)    
Predicted Functional Partners:
Afer_1031
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: stp:Strop_4327 propionyl-CoA carboxylase.
 
 0.997
Afer_0231
PFAM: carboxyl transferase; KEGG: rca:Rcas_4102 carboxyl transferase.
 
 0.985
Afer_0582
PFAM: carboxyl transferase; KEGG: saq:Sare_0802 carboxyl transferase.
 
 0.985
Afer_1346
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: saq:Sare_0033 propionyl-CoA carboxylase.
 
 0.985
Afer_1458
PFAM: Amidase; KEGG: sen:SACE_2834 secreted amidase.
    
 0.894
Afer_1033
PFAM: protein of unknown function DUF1446; KEGG: mjl:Mjls_3217 hypothetical protein.
  
  
 0.871
Afer_1034
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: stp:Strop_3459 enoyl-CoA hydratase/isomerase.
 
 
 0.848
Afer_1029
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: mab:MAB_1851 acyl-CoA dehydrogenase FadE.
  
 
 0.813
Afer_1030
KEGG: sen:SACE_3125 hypothetical protein.
       0.786
Afer_1089
PFAM: Beta-ketoacyl synthase; KEGG: drm:Dred_2070 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.779
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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