Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1040PFAM: regulatory protein TetR; Tetracyclin repressor domain protein; KEGG: ace:Acel_0040 TetR family transcriptional regulator. (219 aa)    
Predicted Functional Partners:
Afer_1039
PFAM: Chloride channel core; KEGG: rha:RHA1_ro05905 chloride channel transporter.
       0.531
Afer_1041
L-lactate dehydrogenase (cytochrome); PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: sen:SACE_5887 L-lactate dehydrogenase.
     
 0.485
Afer_0350
ATPase involved in chromosome partitioning; KEGG: fre:Franean1_0335 anion-transporting ATPase.
  
     0.435
Afer_0712
TIGRFAM: HhH-GPD family protein; PFAM: HhH-GPD family protein; KEGG: sma:SAV_4172 hypothetical protein.
  
    0.429
Afer_0072
PFAM: transcriptional activator domain; KEGG: mva:Mvan_1815 transcriptional regulator.
  
   
 0.428
Afer_1042
Hypothetical protein.
       0.412
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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