STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1053PFAM: biotin/lipoate A/B protein ligase; KEGG: cts:Ctha_0128 biotin/lipoate A/B protein ligase. (357 aa)    
Predicted Functional Partners:
Afer_1055
PFAM: glycine cleavage H-protein; KEGG: sto:ST1894 glycine cleavage system H protein.
 
 
 0.928
Afer_1052
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cts:Ctha_0126 radical SAM domain protein.
 
     0.916
Afer_1054
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cts:Ctha_0127 radical SAM domain protein.
 
     0.914
Afer_1056
PFAM: biotin/lipoate A/B protein ligase; KEGG: cts:Ctha_0125 biotin/lipoate A/B protein ligase.
 
     0.912
Afer_0825
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sth:STH413 pyruvate dehydrogenase E2.
 
 0.726
Afer_0718
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: fre:Franean1_1779 2-oxoglutarate dehydrogenase E2 component.
 
 0.677
gcvH
Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.675
Afer_0826
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: gka:GK1061 dihydrolipoamide dehydrogenase.
 
  
 0.603
Afer_0717
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; KEGG: ace:Acel_0936 dihydrolipoamide dehydrogenase.
 
  
 0.599
Afer_0974
PFAM: glycine cleavage H-protein; KEGG: aae:aq_944 glycine cleavage system protein H.
 
 
 0.591
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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