Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_1060PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sgr:SGR_3233 putative ABC-transporter ATP- binding protein. (230 aa)    
Predicted Functional Partners:
Afer_1058
PFAM: protein of unknown function DUF214; KEGG: nca:Noca_2867 hypothetical protein.
  
 
 0.934
Afer_1311
PFAM: protein of unknown function DUF214; KEGG: lxx:Lxx03110 integral membrane protein.
 
 
 0.906
Afer_1059
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nca:Noca_2866 ABC transporter related.
 
    
0.819
Afer_1207
KEGG: sma:SAV_4866 hypothetical protein.
   
 
 0.646
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   
 0.629
Afer_0778
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: acr:Acry_2202 ABC transporter related.
  
     0.619
map
Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
 
     0.495
Afer_0082
Histidine--tRNA ligase; PFAM: tRNA synthetase class II (G H P and S); KEGG: cms:CMS_2457 histidyl-tRNA synthetase.
  
   
 0.492
cysS
KEGG: hha:Hhal_0107 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.487
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
   
 0.472
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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