Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1064PFAM: protein of unknown function DUF1212; KEGG: rha:RHA1_ro04718 amino acid export carrier protein. (478 aa)    
Predicted Functional Partners:
lipB
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
       0.684
Afer_0087
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: rxy:Rxyl_0021 serine/threonine protein kinase.
       0.599
Afer_0088
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: kra:Krad_0072 protein kinase.
       0.599
Afer_1553
PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: ace:Acel_0986 serine/threonine protein kinase.
       0.599
Afer_0670
KEGG: tfu:Tfu_0325 hypothetical protein.
  
     0.571
Afer_1163
PFAM: Heavy metal transport/detoxification protein; KEGG: mjl:Mjls_4497 heavy metal transport/detoxification protein.
     
 0.548
Afer_1063
KEGG: ooe:OEOE_0191 hypothetical protein.
       0.513
Afer_1065
PFAM: major facilitator superfamily MFS_1; KEGG: nca:Noca_3966 major facilitator transporter.
     
 0.461
Afer_0283
KEGG: mab:MAB_2457c hypothetical protein.
  
     0.457
Afer_0183
PFAM: Transglycosylase domain protein; KEGG: fre:Franean1_0215 transglycosylase domain- containing protein.
 
     0.432
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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