Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Afer_1101KEGG: saq:Sare_1110 diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: GGDEF domain containing protein; EAL domain protein. (1092 aa)    
Predicted Functional Partners:
Afer_0182
KEGG: dge:Dgeo_2370 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
 0.808
Afer_1401
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: azo:azo1486 conserved hypothetical signaling protein.
 
  
 0.802
Afer_1731
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: kra:Krad_2441 diguanylate phosphodiesterase.
 
  
 0.802
Afer_0022
Diguanylate phosphodiesterase; PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: bln:Blon_0041 hypothetical protein.
 
  
 0.800
Afer_1469
KEGG: eba:ebA6041 signal transducer protein; TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein.
 
 
0.579
Afer_1102
TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: ade:Adeh_2848 LigA; Belongs to the GcvT family.
       0.559
Afer_1191
KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein.
 
 
0.474
Afer_0224
Diguanylate cyclase; KEGG: xca:xccb100_3008 putative sensor protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
 0.430
Afer_1470
Diguanylate cyclase; KEGG: cti:RALTA_B0100 putative diguanylate cyclase (GGDEAF) and C-di-GMP phosphodiesterase (EAL domain) with CHASE and PAS domains; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
0.429
Afer_1078
Diguanylate cyclase; KEGG: azo:azo2612 GAF/GGDEF-domain containing protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein.
 
 
0.426
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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