STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1123PFAM: Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; transferase hexapeptide repeat containing protein; KEGG: tfu:Tfu_1394 mannose-1-phosphate guanylyltransferase. (854 aa)    
Predicted Functional Partners:
Afer_1766
PFAM: sugar isomerase (SIS); KEGG: dau:Daud_0299 bifunctional phosphoglucose/phosphomannose isomerase.
 
 0.963
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.943
Afer_0738
PFAM: Nucleotidyl transferase; KEGG: rxy:Rxyl_1624 nucleotidyl transferase.
 
 
0.938
Afer_1768
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: fre:Franean1_5858 phosphomannomutase/phosphoglucomutase.
  
 
 0.926
Afer_0733
TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; KEGG: fal:FRAAL1228 glucose-1-phosphate thymidylyltransferase (dTDP-glucose synthase) (dTDP- glucose pyrophosphorylase) (sugar-nucleotidylation enzyme).
 
  
0.912
Afer_0540
PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; KEGG: chu:CHU_3843 dTDP-4-dehydrorhamnose 3,5- epimerase.
  
 
 0.910
Afer_0107
PFAM: Methyltransferase type 11; glycosyl transferase group 1; Methionine biosynthesis MetW protein; Methyltransferase type 12; KEGG: pcu:pc1183 putative mannosyltransferase.
 
 
 0.828
Afer_0735
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
  
 0.820
Afer_0734
TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: fra:Francci3_1669 dTDP-glucose 4,6- dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.818
Afer_0166
TIGRFAM: transketolase; fructose-1,6- bisphosphatase, class II; PFAM: GlpX family protein; Transketolase domain protein; Transketolase central region; KEGG: ttj:TTHA0108 transketolase; Belongs to the transketolase family.
  
 
 0.816
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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