STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1129PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: mgm:Mmc1_0245 cytochrome c biogenesis protein, transmembrane region. (270 aa)    
Predicted Functional Partners:
Afer_1710
PFAM: Redoxin domain protein; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thioredoxin domain; KEGG: ttj:TTHA1728 hypothetical protein.
 
  
 0.792
Afer_0338
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: mgm:Mmc1_3503 periplasmic protein thiol-- disulphide oxidoreductase DsbE.
 
  
 0.682
Afer_0334
PFAM: cytochrome c assembly protein; KEGG: nca:Noca_1955 cytochrome c assembly protein.
  
  
 0.679
Afer_0251
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sus:Acid_3181 uroporphyrinogen-III C- methyltransferase / uroporphyrinogen-III synthase; Belongs to the precorrin methyltransferase family.
  
    0.645
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.642
Afer_1128
PFAM: protein of unknown function DUF151; KEGG: tfu:Tfu_1396 hypothetical protein.
       0.608
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.571
Afer_1130
PFAM: major facilitator superfamily MFS_1; KEGG: sgr:SGR_469 major facilitator superfamily permease.
  
    0.552
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: dol:Dole_1545 glutamate-1-semialdehyde-2,1- aminomutase.
  
  
 0.528
Afer_1983
PFAM: aminotransferase class-III; KEGG: nca:Noca_3921 aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.528
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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