STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1131KEGG: sco:SCO1215 integral membrane protein. (327 aa)    
Predicted Functional Partners:
Afer_1826
PFAM: Rieske [2Fe-2S] domain protein; KEGG: fal:FRAAL5110 ubiquinol-cytochrome c reductase iron-sulfur subunit (Rieske iron-sulfur protein).
 
    0.797
Afer_1827
PFAM: cytochrome c class I; KEGG: fre:Franean1_1810 cytochrome c class I.
  
     0.744
Afer_1825
PFAM: Cytochrome b/b6 domain; KEGG: fre:Franean1_1812 cytochrome b/b6 domain- containing protein.
 
    0.743
Afer_0193
PFAM: cytochrome oxidase assembly; KEGG: fra:Francci3_1653 cytochrome oxidase assembly.
 
   
 0.694
Afer_1828
PFAM: cytochrome c oxidase subunit III; KEGG: mjl:Mjls_3302 cytochrome c oxidase, subunit III.
 
  
 0.589
Afer_1130
PFAM: major facilitator superfamily MFS_1; KEGG: sgr:SGR_469 major facilitator superfamily permease.
       0.572
Afer_1824
Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
  
 0.531
Afer_1129
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: mgm:Mmc1_0245 cytochrome c biogenesis protein, transmembrane region.
 
     0.501
Afer_0694
PFAM: major facilitator superfamily MFS_1; KEGG: ace:Acel_1472 major facilitator transporter.
  
     0.482
Afer_0114
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
     0.481
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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