STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1139PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: sma:SAV_7489 hypothetical protein. (209 aa)    
Predicted Functional Partners:
Afer_1934
KEGG: bvi:Bcep1808_7294 tungstate/molybdate binding protein.
  
     0.608
Afer_1138
KEGG: ttj:TTHA0546 hemolysin; TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein.
       0.563
Afer_1136
SMC domain protein; May be involved in recombinational repair of damaged DNA.
       0.559
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.559
Afer_1035
PFAM: amino acid permease-associated region; KEGG: acr:Acry_0648 amino acid permease-associated region.
  
    0.536
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
   0.500
Afer_0781
KEGG: acr:Acry_2205 extracellular ligand-binding receptor.
 
     0.496
Afer_0196
PFAM: Peptidase S53 propeptide; KEGG: cac:CAC0625 periplasmic aspartyl protease.
  
     0.491
Afer_0081
PFAM: Peptidase S53 propeptide; KEGG: cac:CAC0625 periplasmic aspartyl protease.
  
     0.490
Afer_1132
PFAM: peptidase M50; KEGG: eli:ELI_03495 hypothetical protein.
     
 0.486
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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