STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Afer_1140PFAM: major facilitator superfamily MFS_1; KEGG: rxy:Rxyl_2414 major facilitator superfamily MFS_1. (391 aa)    
Predicted Functional Partners:
Afer_1459
KEGG: stp:Strop_0704 hypothetical protein.
  
     0.671
Afer_1291
PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: fre:Franean1_2773 XRE family transcriptional regulator.
  
     0.645
Afer_1562
PFAM: protein of unknown function DUF501; KEGG: rxy:Rxyl_0915 hypothetical protein.
  
     0.559
Afer_0039
KEGG: ace:Acel_2136 hypothetical protein.
  
     0.540
Afer_0114
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
     0.506
Afer_0832
PFAM: alpha/beta hydrolase fold; KEGG: mjl:Mjls_4806 alpha/beta hydrolase fold.
  
     0.489
Afer_0577
KEGG: oih:OB1441 hypothetical protein.
  
     0.460
Afer_1882
KEGG: ace:Acel_0470 hypothetical protein.
  
     0.441
Afer_1430
KEGG: nca:Noca_2000 hypothetical protein.
  
     0.440
Afer_1141
PFAM: extracellular solute-binding protein family 5; KEGG: saq:Sare_2145 extracellular solute-binding protein.
       0.426
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.