Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
Afer_1145TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator; KEGG: ace:Acel_0412 cell envelope-related transcriptional attenuator. (543 aa)    
Predicted Functional Partners:
Afer_1146
PFAM: pyruvate carboxyltransferase; KEGG: fre:Franean1_3719 pyruvate carboxyltransferase.
       0.664
Afer_1195
KEGG: scl:sce0507 hypothetical protein.
  
     0.634
Afer_1144
PFAM: extracellular solute-binding protein family 5; KEGG: saq:Sare_2145 extracellular solute-binding protein.
 
     0.596
Afer_1442
PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; KEGG: mjl:Mjls_5269 hypothetical protein.
 
     0.545
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
     0.530
Afer_2033
PFAM: glucose inhibited division protein; KEGG: similar to glucose inhibited division protein B (gidB); K03501 glucose inhibited division protein B.
  
     0.526
Afer_2034
PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KEGG: efa:EF3330 jag protein, putative.
  
     0.482
Afer_0256
PFAM: metallophosphoesterase; KEGG: pzu:PHZ_c0307 3',5'-cyclic-nucleotide phosphodiesterase.
  
     0.479
Afer_0848
PFAM: protein of unknown function UPF0052 and CofD; KEGG: fal:FRAAL4591 hypothetical protein.
  
     0.471
Afer_1023
KEGG: afw:Anae109_1828 hypothetical protein.
 
     0.461
Your Current Organism:
Acidimicrobium ferrooxidans
NCBI taxonomy Id: 525909
Other names: A. ferrooxidans DSM 10331, Acidimicrobium ferrooxidans DSM 10331, Acidimicrobium ferrooxidans ICP, Acidimicrobium ferrooxidans str. DSM 10331, Acidimicrobium ferrooxidans strain DSM 10331
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